Thuflep Side Effects: A Guide For Patients

ThuFLEP is a laser prostate treatment that removes enlarged prostate tissue to improve urinary flow. As with any procedure, side effects can occur, and recovery experiences vary between individuals.

This guide covers what you might experience after ThuFLEP surgery, from immediate recovery through to long-term considerations, helping you prepare for your healing journey.

What Is ThuFLEP Surgery?

ThuFLEP uses a thulium fiber laser to remove excess prostate tissue that blocks urine flow. The procedure is performed through the urethra (the tube that carries urine from your bladder), so no external incisions are required.

For men with larger prostates or more severe symptoms, your doctor may recommend other options, such as HoLEP (Holmium Laser Enucleation of the Prostate), which removes excess tissue more completely.

Common Side Effects After ThuFLEP

It is normal to experience side effects as your body heals and adjusts following ThuFLEP treatment. These can be grouped into immediate effects in the first few days and temporary urinary changes during the short-term recovery period.

Side Effects in the First Few Days

The first few days after ThuFLEP often involve side effects related to tissue healing and catheter use.

  • Blood in Urine (Haematuria): Pink or red-tinged urine is common for several days as the treated prostate tissue heals.
  • Catheter Discomfort: The temporary drainage tube may cause bladder spasms or pressure sensations. This usually settles once the catheter is removed, typically within 1 to 2 days.
  • Pelvic Discomfort: Aching or soreness around the prostate area is common and generally improves with prescribed pain relief.
  • Fatigue: Feeling more tired than usual can occur as your body focuses energy on healing.

Temporary Urinary Changes During Recovery

In the weeks following surgery, your body continues to adjust to the widened urinary passage. These changes usually improve within 2 to 6 weeks.

  • Frequent Urination: You may need to urinate more often than usual as your bladder adapts to the improved flow.
  • Urgency Sensations: Sudden, strong urges to urinate can happen as swelling reduces and bladder function stabilises.
  • Burning During Urination: Stinging sensations while passing urine are common as the urethra heals.
  • Intermittent Bleeding: Light streaks of blood in the urine may continue for several weeks, especially after physical activity.

Long-Term Considerations

Some men notice changes in urinary or sexual function after ThuFLEP, with certain effects being long-term.

  • Retrograde ejaculation: Semen may travel backward into the bladder during climax rather than out through the penis, which affects fertility but not physical sensation
  • Reduced ejaculate volume: The amount of fluid released during ejaculation may decrease permanently
  • Occasional bleeding episodes: Light bleeding may happen months later, particularly during illness or after straining

When to Seek Medical Attention

Contact your doctor if you experience:

  • Heavy bleeding: Bright red blood or clots that persist despite rest and hydration
  • Inability to urinate: Complete difficulty passing urine, which may indicate swelling or blockage
  • Signs of infection: Fever, chills, or worsening burning pain
  • Worsening pain: Severe or increasing discomfort that does not improve with prescribed treatment

Conclusion

Most side effects after ThuFLEP are temporary and manageable, with significant improvement in urinary symptoms for many men.

If you experience concerning symptoms or would like to discuss BPH treatment options such as HoLEP, schedule a consultation with our urology doctor in Singapore to assess the most suitable approach for your condition.

Dr. Lie Kwok Ying - LKY Urology

Dr. Lie Kwok Ying

BA MB BChir (Cantab)|MRCS (Edin)|MMEd (Surg)|FRCS (Glasg)(Urol)|FAMS

Dr. Lie Kwok Ying is a Senior Consultant Urologist and pioneered the use of HoLEP (Holmium Enucleation of Prostate) for benign prostatic hyperplasia (BPH) in Singapore.

He graduated from Queens’ College in Cambridge University with triple First Class Honours and subsequently qualified in 2001 with degrees in Medicine and Surgery.

Clinical Interests in Urology

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