Andropause Treatment in Singapore

Andropause treatment encompasses medical interventions addressing the symptoms and effects of declining testosterone levels in ageing men. Unlike female menopause, which occurs relatively quickly, andropause is a gradual process where testosterone levels decrease by approximately 1-2% per year after age 30. This natural decline can lead to physical, emotional, and sexual health changes that significantly impact daily life.

Treatment for andropause primarily focuses on testosterone replacement therapy (TRT), which aims to restore testosterone levels to a healthy range. This medical intervention involves supplementing the body’s natural testosterone production through various delivery methods, including injections, gels, patches, or pellets. Beyond hormone replacement, comprehensive andropause treatment may include lifestyle modifications, nutritional support, exercise programmes, and management of related health conditions such as osteoporosis, cardiovascular health, and metabolic syndrome.

The goal of andropause treatment is to restore hormonal balance and alleviate symptoms that interfere with quality of life, not to artificially elevate testosterone beyond normal levels. Treatment is personalised based on individual hormone levels, symptoms, overall health status, and personal preferences.

Ideal Candidates

• Men experiencing persistent symptoms of low testosterone including fatigue, decreased libido, erectile dysfunction, mood changes, or reduced muscle mass
• Individuals with laboratory-confirmed low testosterone levels (typically below 300 ng/dL)
• Men aged 40 and above experiencing gradual onset of andropause symptoms
• Patients who have undergone comprehensive medical evaluation to rule out other causes of symptoms
• Individuals committed to regular monitoring and follow-up care
• Men seeking to improve their quality of life and overall well-being through medical intervention
• Patients without contraindications to hormone replacement therapy

Contraindications

• Active prostate cancer or breast cancer
• Severe untreated sleep apnoea
• Uncontrolled heart failure or recent cardiovascular events
• Elevated red blood cell count (polycythaemia)
• Severe lower urinary tract symptoms
• Men planning to father children in the near future (as TRT can affect fertility)
• Untreated or uncontrolled medical conditions that could be worsened by testosterone therapy

A thorough medical evaluation by an experienced endocrinologist or men’s health specialist is essential to determine suitability for andropause treatment. This assessment includes comprehensive blood tests, physical examination, and review of medical history to ensure safe and appropriate treatment planning.

Testosterone Injections

Intramuscular testosterone injections are one of the most established methods of hormone replacement. These injections, typically administered every 2-4 weeks or as long-acting formulations every 10-14 weeks, provide consistent testosterone levels. The treatment involves injection of testosterone esters into large muscle groups, usually the gluteal or thigh muscles. This method offers reliable absorption and allows for precise dosing adjustments based on individual response and blood test results.

Transdermal Testosterone Gels

Daily application of testosterone gel provides a convenient and non-invasive treatment option. The gel is applied to clean, dry skin on the shoulders, upper arms, or abdomen, where it absorbs gradually throughout the day. This method mimics the body’s natural testosterone production pattern and allows for easy dose adjustments. Patients must take precautions to avoid skin-to-skin transfer to partners or children.

Testosterone Patches

Transdermal patches offer another non-invasive option, delivering testosterone through the skin over 24 hours. Patches are typically applied daily to different skin sites to prevent irritation. This method provides steady hormone levels and eliminates the need for injections, though some patients may experience skin reactions at application sites.

Technology & Equipment Used

Modern andropause treatment utilises pharmaceutical-grade testosterone preparations and monitoring techniques. Regular blood tests using high-sensitivity assays track testosterone levels, haematocrit, PSA, and other relevant markers. Some clinics employ body composition analysis technology to monitor changes in muscle mass and body fat distribution during treatment.

Pre-Treatment Preparation

Before initiating andropause treatment, patients undergo comprehensive evaluation including detailed medical history, physical examination, and laboratory tests. Blood work typically includes total and free testosterone levels, complete blood count, liver function tests, lipid profile, and prostate-specific antigen (PSA). Additional tests may include bone density scanning and cardiovascular assessment. Patients discuss treatment goals, potential risks and benefits, and receive education about the selected treatment method. Any underlying health conditions are addressed, and baseline measurements are documented for future comparison.

During the Procedure

The treatment administration varies by method chosen. For injections, patients visit the clinic where trained healthcare professionals administer the testosterone injection using proper sterile technique. The process takes only a few minutes and involves minimal discomfort. For gel or patch applications, patients receive thorough instruction on proper application technique, timing, and safety precautions during their initial consultation. The first application may be supervised to ensure correct technique.

Immediate Post-Treatment

Following injection administration, patients are observed briefly for any immediate reactions, though these are rare. Instructions are provided regarding potential injection site soreness and activity recommendations. For topical treatments, patients learn about absorption time, when to shower or swim, and how to prevent transfer to others. All patients receive written instructions, emergency contact information, and schedule their next appointment for monitoring. Initial symptom diaries may be provided to track treatment response.

First 24-48 Hours

After testosterone injection, mild soreness at the injection site is common and can be managed with gentle massage and over-the-counter pain relief if needed. Normal activities can typically resume immediately. For topical treatments, patients should allow adequate absorption time before dressing and avoid swimming or heavy sweating for several hours after application. Some patients may notice increased energy or mood improvements within days, though full benefits typically develop over weeks to months.

First Week

During the initial week of treatment, patients should monitor for any unusual symptoms while maintaining their regular routine. Energy levels may begin to improve, and some men notice enhanced mood or mental clarity. Maintain consistent application times for topical treatments and follow all safety guidelines. Any concerns or unexpected reactions should be reported to the healthcare provider promptly.

Long-term Recovery

Full therapeutic benefits of andropause treatment typically develop over 3-6 months. Regular monitoring appointments every 3-6 months assess treatment effectiveness, adjust dosing if needed, and screen for potential side effects. Long-term management includes annual comprehensive health evaluations, ongoing symptom assessment, and lifestyle optimisation. Many patients report sustained improvements in energy, libido, muscle mass, bone density, and overall quality of life with continued treatment.

Evidence-based benefits of appropriate andropause treatment include improved energy levels and reduced fatigue, allowing men to maintain active lifestyles and productivity. Many patients experience enhanced libido and sexual function, including improved erectile quality and sexual satisfaction. Treatment often leads to increased muscle mass and strength, along with reduced body fat, particularly abdominal adiposity.

Cognitive benefits may include improved mood, reduced irritability, enhanced memory and concentration, and decreased risk of depression. Bone density typically improves with treatment, reducing osteoporosis risk and potential fractures. Cardiovascular health markers may improve, including better lipid profiles and insulin sensitivity. Overall quality of life scores consistently improve in properly selected and monitored patients, with many men reporting feeling more like their younger selves in terms of vitality and well-being.

Common Side Effects

Acne or oily skin may develop, particularly with higher doses, and can usually be managed with appropriate skincare. Some patients experience increased red blood cell production, requiring dose adjustment or therapeutic phlebotomy. Fluid retention causing mild ankle swelling may occur initially but often resolves. Sleep apnoea may worsen in susceptible individuals, requiring assessment and management. Breast tissue sensitivity or mild enlargement can occur but is usually temporary.

Rare Complications

Cardiovascular events remain a theoretical concern requiring careful patient selection and monitoring. Prostate enlargement or accelerated growth of undetected prostate cancer is possible, emphasising the importance of regular PSA monitoring. Testicular atrophy may occur with long-term use due to suppression of natural production. Liver problems are extremely rare with modern preparations but require monitoring.

Our experienced specialists minimise these risks through careful patient selection, appropriate dosing, regular monitoring, and prompt management of any side effects. The benefits of treatment typically outweigh the risks in properly selected patients.

Andropause treatment costs vary based on the chosen delivery method, frequency of administration, required monitoring tests, and duration of treatment. Injectable testosterone typically requires less frequent administration but involves clinic visits, while daily topical applications offer convenience but may have higher ongoing medication costs. Initial evaluation costs include comprehensive consultation, physical examination, and baseline laboratory tests.

Ongoing expenses encompass regular monitoring blood tests, follow-up consultations, and the testosterone medication itself. Additional costs may include management of side effects or complementary treatments. While quality care requires investment, many patients find the improvements in quality of life, productivity, and relationships provide significant value. Our clinic provides transparent pricing information during consultation to help patients make informed decisions about their treatment options.